So, I made it to Coast of Opportunity, and took the Invaders from the Sea quest. It's rather unclear on the instructions ;-) but it gave me 3 buttons, one of which says "only usable on pirates. When used on a target below 50% health, a Fresh Sample will be obtained. Lasts for 6 seconds." Then there's a button to go to a storage device, and a button to deliver the sample. Looks like I'm supposed to injure a pirate, then click all 3 buttons in quick succession.
The trouble is, I can't make the combination work. I'm unclear whether or not I even _have_ a "fresh sample", and I've never had one by the time I press button 3. It's always "skill requirement error - missing required buff". Perhaps the "below 50%" is inaccurate? Perhaps the appropriate target is not the "Lurking Pirate" all over the camp - but when I try other things, I get errors earlier in the sequence.
[Update - I disarmed myself to keep the targets from dying on me. This allows me to be sure of their % damage when I do 'alt 1'. Now I'm getting 'target error' from both Lurking pirates and sly pirates, and as far as I can tell, there are no other 'pirates' in range.]
[Update 2 - found fierce northern pirates in a brawl near the camp gates. No 'target error' and some are close enough for the tele. But no joy even now - the sample expires during the tele?!?]
[Update 3 - got one - apparently very fast clicking is key, plus lots of luck]