Besides buying them on AH, the easiest way to get production runes is twink a new alt with 2-3 dirty DOD statted pieces of gear and have him attack mobs about 7-8 level too high (which works with minimal danger due to twinking). Almost every drop is 3 runes, from blends on FA bats, Activates on Bandits, etc. When he levels too high - remove alt, pass gear to new alt, rinse, repeat.
As of now, there is no easy way to get V that I know of. III drops all over, IV in instances from bosses. V come from bags, but they are a pain to get. Would be nice if higher level bosses droped Vs, or maybe higher rank runes.
Both should be revamped, I agree.
Agree with vfwiffo here... I can get about 800 Activate runes in an hour if I'm on a good roll.
III runes are all but irrelevant now, and will be even more so once they reactivate Eve; that's a good thing. The game needs to progress. Being stuck with garbage rune drops, low level ammunition, and abysmal pet egg drops from magic cavies in the new zone are simply pathetic. Every 20 levels or so the mobs should increase the level of rune they drop, and boss rune drops should be one level ahead of mobs. I know that for me, runes are becoming less and less relevant, which makes me LESS inclined to spend transmuter chargers on tiering/combining them. If you offer IV & V runes as regular loot drops, I'm sure people would be much more inclined to create VII & VIII runes. Anything lower than those levels of runes just feel like a drop in the ocean of huge stats out there right now.
Wow, sorry about the long paragraph... don't know where all that came from :p.
As to production runes, I think the suggestion of selling them for gold is a good idea. However, they were originally included as drops for a reason (though I don't know exactly what that reason was), so rather than a straight up buy-them-for gold idea, how about you can exchange any production rune for a rune of your choice, for a small fee?