/Scout gets the most base attributes and a second slot for hatred runes due to the additional item, and the spot-skills are really nice. so aggro is pretty easy on your side with that one. has higher base damage on Holy Strike.
/warrior excels if youre strong enough to play with 2H-Axe using whirlwind shield macro, and the damage reduction skills are nice, whole lot of parry.
/priest is usually underestimated but probably the ultimate survivor (better -%pdmg shield skill, and the additional immune aura from the priest itself), and its aggro reduction buff excels with higher -%aggro already built in on your groups DPS because the more reduction they already have, it gets even more easy with your debuff on top ;-) (take 3 runes a 24% + 25% of your buff and the DPS will only do 3% of their initial aggro)
/rogue is a bit like warrior, excels when you can play with a second weapon instead of a shield, but with a lot of dodging instead of parrying. has a fixed critrate on Holy Strike.
/mage - dont have experience at all so i cant comment.
TL,DR: Every combination makes a good tank if you know what you're doing, so choose what fits you best.