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For PvP the best healing combo is easily and by far the Priest/Knight. Stat with lots of stam/defense and wis/defense and stam/wis and you'll be an absolute beast in siege.
The only reason I started straying from def a bit was that rogues like bleeding black can burn you down no matter the def, so it is better just to stack hp.
I feel like if we ever get that 90% reduction i'm going to really love my defense. And as long as I stay over 100K HP unbuffed i'm easily geared enough for the current content.